French beauty brand Biologique Recherche is every beauty editor's best kept secret. Its potent formulations are the product of the brand's clinical approach to skincare, investing in cutting-edge research and dedication to quality production. Some may have heard of the brand's legendary P50 toners, which speed up the skin's natural turnover process using chemical exfoliants, and which are coveted by celebrities and beauty gurus alike. The problem with Biologique Recherche's products is that they can be diffiuclt to get your hands on, as the brand only partners with select trusted aesthetic clinics, spas, and dermatologists. It has not been unheard of for beauty junkies to come home with bags full of Biologique Recherche products after a trip to Paris, the brand's home city. But now, all of that is unnecessary, as the brand has partnered with one of Singapore's top aesthetic and facial centres, Freia Aesthetics, to launch its products. And best of all—Freia Aesthetics is also the first in Singapore to carry one of Biologique Recherche's most potent potions to date, La Grande Crème.
La Grande Crème works based on the discovery that certain ingredients can affect the epigenetic expression of certain genes in human skin cells, blocking cells' ageing and reversing existing damage. Epi-genetics ('epi' meaning over, outside, or around in Greek) is the study of how genes are expressed in the human body based on environmental factors, without alterations to the actual genetic sequence. While the science is complex, scientists divide genetic expression into two: constitutive expression and induced expression. Constitutive expression is the part of the genes that is always expressed, no matter the context, while induced expression is the part of gene expression that only occurs when specific signals are received. This is best illustrated by two identical twins, who may look physically alike, but one looks noticeably older thanks to certain lifestyle choices.