As COVID-19 cases surge, albeit with the supposedly 'milder' symptoms of the Omicron variant, many believe that coronavirus will soon be a problem of the past—no more than the seasonal flu. But what does the science say?
Now 22 months since the World Health Organisation (WHO) declared COVID-19 a global pandemic, nations across the globe continue to battle against rising cases like never before. In large part, this is due to Omicron, the newest SARS-CoV-2 variant recognised as a Variant of Concern (VoC) by WHO and the United States Centers for Disease Control and Prevention (CDC). “The Omicron variant can be three to five times as highly transmissible as that of Delta” explains Dr Rontegene Solante, infectious diseases specialist.
When the Philippine Department of Health (DOH) confirmed the country’s first cases of Omicron on the 15th of December 2021, they had only reported 237 new cases of COVID-19. Less than one month later, the Philippines has now broken its record with 33,169 new cases and a 46 per cent positivity rate on the 10th of January, 2022, patterns that have continued to rise in recent weeks—however, 97.1 per cent of these cases are mild or asymptomatic. With such trends observed worldwide, many speculate that Omicron signals the beginning of the pandemic’s end. After all, it is mutually advantageous to both the virus and its host for the virus to be less deadly: as non-living agents, viruses rely on host cells in order to replicate, which is why viruses infect hosts to begin with.
This begs the question: do viruses become less deadly in order to survive, and perhaps more importantly, is this the case with the SARS-CoV-2?
See also: From 'Poblacion Girl' to The Surge of Covid-19 Cases: Is Omicron Really the 'Beginning of the End'?
Virus mutation: what is it, and why does it occur?
Like other RNA viruses, SARS-CoV-2 (the coronavirus that causes COVID-19) is highly prone to genetic mutations. As the virus makes replicas of itself, the resulting copies will likely have ‘errors’ in their genetic code, meaning they will not be exact replicas of the original. This imperfect replication results in numerous virus variants with distinct genetic codes. For the most part, these mutations have minimal or neutral effects on the virus’s characteristics. However, there are times when these mutations cause dangerous changes in the virus’s pathogenic properties. In these cases, public health bodies like WHO may identify these variants as a Variant of Interest (VoI) or the more closely-monitored VoC. At the time of writing, WHO identifies five VoCs including Omicron, which joined the list on the 26th of November 2021.
See also: COVID-19 Omicron Variant: Here's Everything You Need to Know