Dr Teo leads the research portfolio at Cancer Research Malaysia, where she and her team spearheaded the largest study of genomic profiles on Asian breast cancers, providing valuable insights into treatment and survival for Asian women. Their efforts contributed to the development of the first investigator-led clinical trial testing new therapies for Asian breast cancer patients. In a pioneering move, Teo initiated the Malaysian Breast Cancer Genetic Study, leading to the identification of genes associated with cancer risk and the creation of the Asian Genetic Risk Calculator.

Her research findings have garnered numerous research grants, including the prestigious Wellcome Trust Collaborative Science Award and the Newton Grant Awards.