After graduating from the California College of the Arts in 1991, Anthony Nazareno began his career in San Francisco under the mentorship of renowned modernist architect Jim Jennings. He later joined Li-Saltzman PC, a New York-based architectural firm that focuses on historic building preservation and conservation. And finally, in 1997, he was able to establish Nazareno Architecture & Design, which was formerly known as the Nazareno+Guerrero Design Consultancy. The firm is known for its bespoke high-end residential architecture and a variety of retail projects.

Anthony and his team of designers often find themselves collaborating with other talented creatives in the industry who bring a layer of depth and character to the architecture. Some of these creatives include artists, landscape architects, interior designers, and on occasion, his sister, designer Rita Nazareno.

In the design industry, Anthony is known for his expressive use of texture and materiality. In an interview with Tatler, he said “When it comes to texture and materiality, my team and I strive for something new and innovative. If a material isn’t readily available here in the Philippines, we try to get in touch with suppliers from abroad who can bring them here.” In 2023, The Banaba Residence, a renovation project done by NAD, was given the recognition of the “Best Living Space” award at the Tatler Home Design Awards. The category acknowledges intuitive design in the most used spaces of the home, the expanse in which we live, dine, converse, entertain, and seek refuge.