But he has an unexpected weapon in his pursuit of perfection: he closely monitors social media to keep an eye on customer reviews of his culinary empire.
The 62-year-old is arguably the doyen of France's "grande cuisine". His eateries currently have 20 Michelin stars, more than any living contemporary, and three of his restaurants have the coveted three-star accolade.
But just as Ducasse—who now boasts more than 30 restaurants across seven countries—blends tradition and modernity in his menus, he sees tech as a way to finesse the dining experience.
It's through social media that he discovered Benoit, his popular New York bistro, was messing up a classic French dish.
"Looking at the customer reviews we realised there was an issue. Everyone was complaining about the roast chicken," Ducasse tells AFP during a visit to Macau.
"It was unbelievable," he recalls, adding that this helped them spot and fix the issue immediately.
That Ducasse personally monitors the social media of all his restaurants is indicative of a man who insists on maintaining control over a sprawling inter-continental business.
"Before we opened here we spent three years choosing every detail. I know every object; there was a lot of personal involvement," Ducasse says of his eponymous restaurant in Macau at the Morpheus, a new 40-storey luxury hotel designed by the late Zaha Hadid that is held together by an eye-catching steel exoskeleton.