How will the royal family respond?
Buckingham Palace did not comment directly on the explosive pre-broadcast excerpts released before Sunday's interview. Weekend reports said they were unlikely to do so afterwards, unless individual members of the royal family were criticised.
Yet they still face tough questions about Meghan's claims she had suicidal thoughts and felt isolated while pregnant, and failed to get any support.
Racism accusations against an unnamed royal are particularly sensitive, with Meghan having been the first senior member to be of mixed race.
Black Lives Matter protests last year sparked calls for an urgent revision of the legacy of the British Empire.
Harry's older brother, William, and his wife Kate, will be watched closely for any response, given their involvement in advocating for better mental health.
See also: Oprah's Royal Interview: 10 Revelations From Meghan Markle & Harry
Who made the racist comment?
Harry vowed never to reveal which member of the royal family asked him about how dark their young son Archie's skin would be. Winfrey said Harry had told her the conversations did not concern his grandmother Queen Elizabeth II, or her husband Prince Philip.
But it has sparked a guessing game that will do little to enhance attempts to portray the royal family as in touch with modern life and attitudes—and could force the monarchy to respond.
See also: Baby Sussex Is Born—Here’s What We Know About Meghan And Harry’s Baby